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• Instructions for online access
• Cover image
• Title Page
• Table of Contents
• Award page
• Copyright
• Dedication
• Contributors
• Preface
• Acknowledgments
• Get the most out of The Developing Human 11th Edition!
• 1 Introduction to Human Development
• Developmental Periods
• Significance of Embryology
• Historical Gleanings
• Genetics and Human Development
• Molecular Biology of Human Development
• Descriptive Terms in Embryology
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 2 First Week of Human Development
• Gametogenesis
• Meiosis
• Spermatogenesis
• Oogenesis
• Comparison of Gametes
• Uterus, Uterine Tubes, and Ovaries
• Female Reproductive Cycles
• Ovarian Cycle
• Menstrual Cycle
• Transportation of Gametes
• Maturation of Sperms
• Viability of Gametes
• Sequence of Fertilization
• Cleavage of Zygote
• Formation of Blastocyst
• Summary of First Week
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 3 Second Week of Human Development
• Completion of Implantation of Blastocyst
• Formation of Amniotic Cavity, Embryonic Disc, and Umbilical Vesicle
• Development of Chorionic Sac
• Implantation Sites of Blastocysts
• Summary of Implantation
• Summary of Second Week
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 4 Third Week of Human Development
• Gastrulation: Formation of Germ Layers
• Primitive Streak
• Notochordal Process and Notochord
• Allantois
• Neurulation: Formation of Neural Tube
• Development of Somites
• Development of Intraembryonic Coelom
• Early Development of Cardiovascular System
• Development of Chorionic Villi
• Summary of Third Week
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 5 Fourth to Eighth Weeks of Human Development
• Phases of Embryonic Development
• Folding of Embryo
• Germ Layer Derivatives
• Control of Embryonic Development
• Highlights of Fourth to Eighth Weeks
• Estimation of Embryonic Age
• Summary of Fourth to Eighth Weeks
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 6 Fetal Period
• Estimation of Fetal Age
• Highlights of Fetal Period
• Expected Date of Delivery
• Factors Influencing Fetal Growth
• Procedures for Assessing Fetal Status
• Summary of Fetal Period
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 7 Placenta and Fetal Membranes
• Placenta
• Parturition
• Umbilical Vesicle
• Allantois
• Multiple Pregnancies
• Summary of Placenta and Fetal Membranes
• Neonatal Period
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 8 Body Cavities, Mesenteries, and Diaphragm
• Embryonic Body Cavity
• Development of Diaphragm
• Summary of Development of Body Cavities, Mesenteries, and Diaphragm
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 9 Pharyngeal Apparatus, Face, and Neck
• Pharyngeal Arches
• Pharyngeal Pouches
• Pharyngeal Grooves
• Pharyngeal Membranes
• Development of Thyroid Gland
• Development of Tongue
• Development of Salivary Glands
• Development of Face
• Development of Nasal Cavities
• Development of Palate
• Summary of Pharyngeal Apparatus, Face, and Neck
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 10 Respiratory System
• Respiratory Primordium
• Development of Larynx
• Development of Trachea
• Development of Bronchi and Lungs
• Summary of Respiratory System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 11 Alimentary System
• Foregut
• Midgut
• Hindgut
• Enteric Nervous System
• Summary of Alimentary System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 12 Urogenital System
• Development of Urinary System
• Development of Suprarenal Glands
• Development of Genital System
• Development of External Genitalia
• Development of Inguinal Canals
• Relocation of Testes and Ovaries
• Summary of Urogenital System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 13 Cardiovascular System
• Early Development of Heart and Blood Vessels
• Later Development of Heart
• Birth Defects of Heart and Great Vessels
• Derivatives of Pharyngeal Arch Arteries
• Fetal and Neonatal Circulation
• Development of Lymphatic System
• Summary of Cardiovascular System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 14 Skeletal System
• Development of Bone and Cartilage
• Development of Joints
• Development of Axial Skeleton
• Development of Appendicular Skeleton
• Summary of Skeletal System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 15 Muscular System
• Development of Skeletal Muscle
• Development of Smooth Muscle
• Development of Cardiac Muscle
• Summary of Muscular System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 16 Development of Limbs
• Early Stages of Limb Development
• Final Stages of Limb Development
• Birth Defects of Limbs
• Summary of Limb Development
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 17 Nervous System
• Development of Nervous System
• Development of Spinal Cord
• Development of Brain
• Birth Defects of Brain
• Development of Peripheral Nervous System
• Development of Autonomic Nervous System
• Summary of Nervous System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 18 Development of Eyes and Ears
• Development of Eyes and Related Structures
• Development of Ears
• Summary of Eye Development
• Summary of Ear Development
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 19 Integumentary System
• Development of Skin and Appendages
• Summary of Integumentary System
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 20 Human Birth Defects
• Classification of Birth Defects
• Teratology: Study of Abnormal Development
• Birth Defects Caused by Genetic Factors
• Birth Defects Caused by Environmental Factors
• Birth Defects Caused by Multifactorial Inheritance
• Summary of Birth Defects
• Clinically Oriented Problems
• Bibliography and Suggested Reading
• 21 Common Signaling Pathways Used During Development
• Intercellular Communication
• Morphogens
• Protein Kinases
• NOTCH-DELTA Pathway
• Transcription Factors
• Epigenetics
• Stem Cells: Differentiation Versus Pluripotency
• Summary of Common Signaling Pathways Used During Development
• Bibliography and Suggested Reading
• Appendix Discussion of Clinically Oriented Problems
• Chapter 1
• Chapter 2
• Chapter 3
• Chapter 4
• Chapter 5
• Chapter 6
• Chapter 7
• Chapter 8
• Chapter 9
• Chapter 10
• Chapter 11
• Chapter 12
• Chapter 13
• Chapter 14
• Chapter 15
• Chapter 16
• Chapter 17
• Chapter 18
• Chapter 19
• Chapter 20
• Index