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• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• PREFACE
• BASIC TISSUES | CELL BIOLOGY
• Chapter 1: EPITHELIUM | CELL BIOLOGY
• CLASSIFICATION OF EPITHELIA (1-1 to 1-4)
• CELL JUNCTIONS (1-10)
• CONNEXIN MUTATIONS
• CYTOSKELETON (1-15)
• CILIOPATHIES
• CELL NUCLEUS (1-25)
• LAMINOPATHIES
• CELL CYCLE (1-31 and 1-32)
• BASIC CONCEPTS OF MEDICAL GENETICS (1-38)
• Chapter 2: EPITHELIAL GLANDS | CELL BIOLOGY
• EPITHELIAL GLANDS
• PLASMA MEMBRANE AND CYTOMEMBRANES
• LYSOSOME STORAGE DISORDERS (Primer 2-E)
• MITOCHONDRIA REPLACEMENT THERAPIES (2-18)
• PEROXISOME BIOGENESIS DISORDERS (PBDs)
• Chapter 3: CELL SIGNALING | CELL BIOLOGY | PATHOLOGY
• CELL SIGNALING MECHANISMS
• APOPTOSIS AND THE IMMUNE SYSTEM
• APOPTOSIS AND NEURODEGENERATIVE DISEASES
• NEOPLASIA (3-17)
• Chapter 4: CONNECTIVE TISSUE
• EHLERS-DANLOS SYNDROME (4-5)
• MARFAN’S SYNDROME
• MOLECULAR BIOLOGY OF TUMOR INVASION (Primer 4-A)
• ADIPOSE TISSUE OR FAT (4-11 and 4-12)
• CARTILAGE (4-13)
• BONE
• OSTEOPOROSIS
• OSTEOPETROSIS AND OSTEOMALACIA
• Chapter 5: OSTEOGENESIS
• OSTEOGENESIS
• BONE FRACTURE AND HEALING (Primer 5-A)
• BONE DISORDERS (5-13)
• RHEUMATOID ARTHRITIS (5-15)
• Chapter 6: BLOOD AND HEMATOPOIESIS
• BLOOD
• ERYTHROBLASTOSIS FETALIS (6-3)
• LEUKOCYTE RECRUITMENT AND INFLAMMATION (6-9)
• MAST CELL, EOSINOPHIL AND ASTHMA (6-10)
• COAGULATION DISORDERS (6-11, 6-12; Primer 6-A)
• HEMOSTASIS AND BLOOD CLOTTING (see Primer 6-A)
• HEMATOPOIESIS
• LEUKEMIAS
• IRON-OVERLOAD DISORDERS (Primer 6-B)
• MEGALOBLASTIC ANEMIA (6-27; see Primer 6-B)
• Chapter 7: MUSCLE TISSUE
• SKELETAL MUSCLE (7-1)
• DISORDERS OF NEUROMUSCULAR SYNAPTIC TRANSMISSION (7-11 and 7-12)
• MUSCULAR DYSTROPHIES (7-14)
• SATELLITE CELLS AND MUSCLE REPAIR (Primer 7-A)
• CARDIAC MUSCLE (7-16 to 7-18)
• MYOCARDIAL INFARCTION (7-19)
• SMOOTH MUSCLE (7-20 and 7-21)
• Chapter 8: NERVOUS TISSUE
• DEMYELINATING DISEASES (8-14)
• NEURODEGENERATIVE DISEASES (8-15 and 8-16)
• Chapter 9: SENSORY ORGANS: VISION AND HEARING
• EYE (9-1)
• EAR
• ORGAN SYSTEMS | PROTECTION OF THE BODY
• Chapter 10: IMMUNE-LYMPHATIC SYSTEM
• COMPONENTS OF THE IMMUNE–LYMPHATIC SYSTEM (10-1 and 10-2)
• ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) (Primer 10-B)
• HYPERSENSITIVITY REACTIONS (10-11)
• INFLAMMATION
• LYMPHOID ORGANS
• LYMPHADENITIS AND LYMPHOMAS (10-18)
• THYMUS
• SPLEEN (10-23 and 10-24)
• SICKLE CELL ANEMIA (10-28)
• ASPLENIA
• CANCER IMMUNOTHERAPY (10-29)
• Chapter 11: INTEGUMENTARY SYSTEM
• ORGANIZATION AND TYPES OF SKIN (11-1)
• WOUND HEALING (11-12)
• PSORIASIS (11-13)
• TUMORS OF THE EPIDERMIS
• CYSTIC FIBROSIS (11-21)
• ORGAN SYSTEMS | BLOOD CIRCULATORY SYSTEMS
• Chapter 12: CARDIOVASCULAR SYSTEM
• THE CARDIOVASCULAR SYSTEM (12-1)
• AORTIC ANEURYSMS
• VASCULITIS (Primer 12-A)
• EDEMA
• HEMORRHAGE
• ATHEROSCLEROSIS (Primer 12-B)
• ANGIOGENESIS AND TUMOR PROGRESSION (Primer12-C)
• THROMBOSIS, EMBOLISM AND INFARCTION (12-14)
• HYPERTENSION (12-15)
• Chapter 13: RESPIRATORY SYSTEM
• THE RESPIRATORY SYSTEM
• CYSTIC FIBROSIS (13-6)
• BRONCHOPULMONARY DISEASES
• ASTHMA (Primer 13-A)
• CHRONIC OBSTRUCTIVE PULMONARY DISEASE (13-18 and 13-19)
• ACUTE RESPIRATORY DISTRESS SYNDROME (13-20 and 13-21)
• LUNG CANCER
• DISORDERS OF THE PLEURA (13-23)
• Chapter 14: URINARY SYSTEM
• THE KIDNEYS (14-1)
• PATHOLOGY OF THE GBM (14-8; Primer 14-A)
• PODOCYTE INJURY (14-11 and Primer 14-A; see 14-8)
• ORGAN SYSTEMS | THE ALIMENTARY SYSTEM
• Chapter 15: UPPER DIGESTIVE SEGMENT
• NON-NEOPLASTIC AND NEOPLASTIC LESIONS OF THE ORAL MUCOSA
• INFECTION WITH Helicobacter pylori (15-17; Primer 15-A)
• Chapter 16: LOWER DIGESTIVE SEGMENT
• SMALL INTESTINE (16-1 to 16-3)
• INFLAMMATORY BOWEL DISEASES (16-18)
• MALABSORPTION SYNDROMES
• LARGE INTESTINE (16-19 and 16-20)
• HIRSCHSPRUNG’S DISEASE (16-23)
• COLORECTAL TUMORIGENESIS (Primer 16-A)
• Chapter 17: DIGESTIVE GLANDS
• STRUCTURE OF A SALIVARY GLAND (17-1 and 17-2)
• PANCREATIC TUMORS
• PANCREATITIS AND CYSTIC FIBROSIS
• LIVER (17-10)
• PERISINUSOIDAL CELLS AND CHRONIC LIVER DISEASE (see 17-18)
• ALCOHOLISM AND FATTY LIVER (ALCOHOLIC STEATOHEPATITIS) (17-19)
• CHRONIC HEPATITIS AND CIRRHOSIS (see 17-18)
• HYPERBILIRUBINEMIA (see Primer 17-A)
• ORGAN SYSTEMS | THE ENDOCRINE SYSTEM
• Chapter 18: NEUROENDOCRINE SYSTEM
• HYPOPHYSIS (18-1)
• GIGANTISM (IN CHILDREN) AND ACROMEGALY (IN ADULTS)
• HYPERPROLACTINEMIA
• INFERTILITY
• HYPOTHYROIDISM
• CUSHING’S DISEASE
• NEUROHYPOPHYSIS
• HYPOTHALAMIC DIABETES INSIPIDUS
• PINEAL GLAND
• PINEALOMAS
• Chapter 19: ENDOCRINE SYSTEM
• THYROID GLAND
• GRAVES’ DISEASE AND HYPOTHYROIDISM (19-4)
• PARATHYROID GLANDS
• DYSFUNCTION OF THE PARATHYROID GLANDS
• CaSR AND Gq/11 MUTATIONS
• ADRENAL (SUPRARENAL) GLANDS
• DYSFUNCTION OF THE ADRENAL CORTEX
• ENDOCRINE PANCREAS
• DIABETES MELLITUS (19-20 and 19-21)
• ORGAN SYSTEMS | THE REPRODUCTIVE SYSTEM
• Chapter 20: SPERMATOGENESIS
• ABSTRACT
• THE TESTES (20-1 and 20-2)
• CONDITIONS AFFECTING MALE FERTILITY
• EPIGENETICS REPROGRAMMING (20-18 to 20-20; see 20-10)
• TESTICULAR TUMORS (20-21)
• Chapter 21: SPERM TRANSPORT AND MATURATION
• DEVELOPMENT OF THE GONADS (Primer 21-A)
• ANDROGEN INSENSITIVITY SYNDROME (AIS)
• STEROID 5α-REDUCTASE 2 DEFICIENCY
• SPERM MATURATION PATHWAY (21-2 and 21-3)
• THE AZOOSPERMIA FACTOR (AZF)
• BENIGN PROSTATIC HYPERPLASIA (21-11; see 21-9)
• PROSTATE CANCER AND TUMOR SUPPRESSOR GENES
• Chapter 22: FOLLICULOGENESIS AND MENSTRUAL CYCLE
• HYPOGONADOTROPIC HYPOGONADISM AND GnRH
• ENDOMETRIOSIS
• CERVICAL CANCER AND HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION (22-17)
• DIAGNOSTIC CYTOPATHOLOGY (see 22-17)
• Chapter 23: FERTILIZATION, PLACENTATION AND LACTATION
• FERTILIZATION
• ABNORMAL PLACENTATION
• GESTATIONAL TROPHOBLASTIC DISEASES (23-14)
• LACTATION
• BENIGN BREAST DISEASES AND BREAST CANCER (23-19; see Primer 23-A)
• INDEX
• Instructions for online access