West’s Respiratory Physiology

Höfundur John B. West; Andrew M. Luks

Útgefandi Wolters Kluwer Health

Snið ePub

Print ISBN 9781975139186

Útgáfa 11

Útgáfuár

7.690 kr.

Description

Efnisyfirlit

  • Cover
  • Title Page
  • Copyright
  • Dedication
  • Preface
  • Animations
  • Contents
  • Chapter 1 Structure and Function—How the Architecture of the Lung Subserves Its Function
  • Blood-Gas Interface
  • Airways and Airflow
  • Blood Vessels and Flow
  • Stability of Alveoli
  • Removal of Inhaled Particles
  • Removal of Material from the Blood
  • Chapter 1: Multiple Choice Questions
  • Chapter 2 Ventilation—How Gas Gets to the Alveoli
  • Lung Volumes
  • Ventilation
  • Anatomic Dead Space
  • Physiologic Dead Space
  • Regional Differences in Ventilation
  • Chapter 2: Multiple Choice Questions
  • Chapter 3 Diffusion—How Gas Gets Across the Blood-Gas Barrier
  • Laws of Diffusion
  • Diffusion and Perfusion Limitations
  • Oxygen Uptake Along the Pulmonary Capillary
  • Measurement of Diffusing Capacity
  • Reaction Rates with Hemoglobin
  • Interpretation of Diffusing Capacity for CO
  • CO2 Transfer Across the Pulmonary Capillary
  • Chapter 3: Multiple Choice Questions
  • Chapter 4 Blood Flow and Metabolism—How the Pulmonary Circulation Removes Gas from the Lung and Alters Some Metabolites
  • Pressures Within Pulmonary Blood Vessels
  • Pressures Around Pulmonary Blood Vessels
  • Pulmonary Vascular Resistance
  • Measurement of Pulmonary Blood Flow
  • Distribution of Blood Flow
  • Active Control of the Circulation
  • Water Balance in the Lung
  • Other Functions of the Pulmonary Circulation
  • Metabolic Functions of the Lung
  • Chapter 4: Multiple Choice Questions
  • Chapter 5 Ventilation-Perfusion Relationships—How Matching of Gas and Blood Determines Gas Exchange
  • Oxygen Transport from Air to Tissues
  • Hypoventilation
  • Diffusion Limitation
  • Shunt
  • The Ventilation-Perfusion Ratio
  • Effect of Altering the Ventilation-Perfusion Ratio of a Lung Unit
  • Regional Gas Exchange in the Lung
  • Effect of Ventilation-Perfusion Inequality on Overall Gas Exchange
  • Distributions of Ventilation-Perfusion Ratios
  • Ventilation-Perfusion Inequality as a Cause of CO2 Retention
  • Measurement of Ventilation-Perfusion Inequality
  • Chapter 5: Multiple Choice Questions
  • Chapter 6 Gas Transport by the Blood—How Gases Are Moved to and from the Peripheral Tissues
  • Oxygen
  • Dissolved O2
  • Combination with Hemoglobin
  • O2 Dissociation Curve
  • Carbon Dioxide
  • CO2 Carriage
  • CO2 Dissociation Curve
  • Acid-Base Status
  • Respiratory Acidosis
  • Respiratory Alkalosis
  • Metabolic Acidosis
  • Metabolic Alkalosis
  • Blood-Tissue Gas Exchange
  • Diffusion
  • Tissue Po2
  • Mixed Venous Po2
  • Chapter 6: Multiple Choice Questions
  • Chapter 7 Mechanics of Breathing—How the Lung Is Supported and Moved
  • Muscles of Respiration
  • Inspiration
  • Expiration
  • Elastic Properties of the Lung
  • Pressure-Volume Curve
  • Compliance
  • Surface Tension
  • Cause of Regional Differences in Ventilation
  • Airway Closure
  • Elastic Properties of the Chest Wall
  • Airway Resistance
  • Airflow Through Tubes
  • Measurement of Airway Resistance
  • Pressures During the Breathing Cycle
  • Chief Site of Airway Resistance
  • Factors Determining Airway Resistance
  • Dynamic Compression of Airways
  • Forced Expiration Test
  • Additional Causes of Uneven Ventilation
  • Tissue Resistance
  • Work of Breathing
  • Work Done on the Lung
  • Total Work of Breathing
  • Mechanics of Positive Pressure Breathing
  • Chapter 7: Multiple Choice Questions
  • Chapter 8 Control of Ventilation—How Gas Exchange Is Regulated
  • Central Controller
  • Brainstem
  • Cortex
  • Other Parts of the Brain
  • Effectors
  • Sensors
  • Central Chemoreceptors
  • Peripheral Chemoreceptors
  • Lung Receptors
  • Other Receptors
  • Integrated Responses
  • Response to Carbon Dioxide
  • Response to Oxygen
  • Response to pH
  • Response to Exercise
  • Ventilatory Control During Sleep
  • Abnormal Patterns of Breathing During Sleep
  • Chapter 8: Multiple Choice Questions
  • Chapter 9 Respiratory System Under Stress—How Gas Exchange Is Accomplished During Exercise, at Low and High Pressures, and at Birth
  • Exercise
  • High Altitude
  • Hyperventilation
  • Polycythemia
  • Other Physiological Changes at High Altitude
  • Permanent Residents of High Altitude
  • O2 Toxicity
  • Absorption Atelectasis
  • Space Flight
  • Increased Pressure
  • Barotrauma
  • Decompression Sickness
  • Inert Gas Narcosis
  • O2 Toxicity
  • Hyperbaric O2 Therapy
  • Polluted Atmospheres
  • Perinatal Respiration
  • Placental Gas Exchange
  • The First Breath
  • Circulatory Changes
  • Respiration in Infancy
  • Mechanics and Airflow
  • Gas Exchange
  • Control of Breathing
  • Chapter 9: Multiple Choice Questions
  • Chapter 10 Tests of Pulmonary Function—How Respiratory Physiology Is Applied to Measure Lung Function
  • Uses of Pulmonary Function Testing
  • Ventilation
  • Forced Expiration
  • Lung Volumes
  • Diffusion
  • Blood Flow
  • Ventilation-Perfusion Relationships
  • Topographical Distribution of Ventilation and Perfusion
  • Inequality of Ventilation
  • Inequality of Ventilation-Perfusion Ratios
  • Blood Gases and pH
  • Mechanics of Breathing
  • Lung Compliance
  • Airway Resistance
  • Closing Volume
  • Control of Ventilation
  • Exercise
  • Chapter 10: Multiple Choice Questions
  • Appendix A—Symbols, Units, and Equations
  • Appendix B—Answers
  • Index
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