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• Cover
• Title Page
• Copyright
• Introduction
• About This Book
• Foolish Assumptions
• Icons Used in This Book
• Beyond This Book
• Where to Go from Here
• Part 1: The Lowdown on Genetics: Just the Basics
• Chapter 1: Welcome to Genetics: Just About Everyone Loves a Good Pair of Genes
• Unwrapping Life’s Secrets
• Classical Genetics: Studying How Traits Are Transmitted within Families
• Molecular Genetics: Diving into DNA Science
• Population Genetics: Studying the Genetics of Groups
• Quantitative Genetics: Exploring the Heredity of Complex Traits
• Chapter 2: Basic Cell Biology
• Entering the World of the Cell
• Exploring Your DNA, Chromosomes, and Genes
• Mitosis: Splitting Up
• Meiosis: Making Cells for Sexual Reproduction
• Chapter 3: Visualize Peas: Discovering the Laws of Inheritance
• Gardening with Gregor Mendel
• Speaking the Language of Inheritance
• Simplifying Inheritance
• Finding Unknown Alleles
• Applying Basic Probability to the Likelihood of Inheritance
• Solving Genetics Problems
• Chapter 4: Law Enforcement: Mendel’s Laws Applied to Complex Traits
• Dominant Alleles Rule … Sometimes
• Alleles Causing Complications
• Making Life More Complicated
• Uncovering More Exceptions to Mendel’s Laws
• Part 2: DNA: The Genetic Material
• Chapter 5: DNA: The Pattern for Life
• Chemical Ingredients of DNA
• Assembling the Double Helix: The Structure of DNA
• Examining Different Varieties of DNA
• Digging into the History of DNA
• Chapter 6: Chromosomes: The Big Picture
• Packaging the Double Helix
• Anatomy of a Chromosome
• Two Chromosomes Are Better than One (or Three)
• Sex Chromosomes: Is It a Boy or Girl?
• Chapter 7: Replication: A Copy Machine for DNA
• Unzipped: Creating the Pattern for More DNA
• How DNA Copies Itself
• Replication in Eukaryotes
• How Circular DNAs Replicate
• Chapter 8: Transcription: Getting Instructions from DNA
• RNA: DNA’s Close Cousin
• Transcription: Copying DNA’s Message into RNA’s Language
• Post-transcription Processing
• Chapter 9: Translating the Genetic Code
• Discovering the Good in a Degenerate
• Meeting the Translating Team
• Taking the Translation Trip
• Proteins Are Powerful
• Chapter 10: Gene Expression: Finding the Right Tool for the Job
• Getting Your Genes Under Control
• To Be Expressed or Not To Be Expressed?
• Regulating Eukaryotic Gene Expression: A Time and Place for Everything
• Controlling Transcription Before It Starts
• Regulation of Gene Transcription: Flipping the Switch
• Post-transcriptional Control
• Gene Control Lost in Translation
• Prokaryotic Gene Expression
• Part 3: Genetics and Your Health
• Chapter 11: What Could Go Wrong: Changes in DNA Sequence
• Heritable or Not Heritable?
• Facing the Consequences of Sequence Variants
• Sorting Out Terminology
• What Causes Sequence Variants?
• Evaluating Options for DNA Repair
• Chapter 12: Chromosome Disorders: It’s All a Numbers Game
• Chromosome Numbers: No More and No Less
• Aneuploidy of the Autosomal Chromosomes
• Aneuploidy of the Sex Chromosomes
• Exploring Variations in Chromosome Structure
• How Chromosomes Are Studied
• Non-Invasive Prenatal Testing for Aneuploidy
• Chapter 13: Taking a Closer Look at the Genetics of Cancer
• Defining Cancer
• Recognizing Cancer as a DNA Disease
• Breaking Down the Types of Cancers
• Chapter 14: Genetic Counseling, Risk Assessment, and Genetic Testing
• Getting to Know Genetic Counselors
• Building and Analyzing a Family Tree
• Autosomal Inheritance: No Differences Among the Sexes
• Found on Sex Chromosomes: Sex-linked Inheritance
• Testing for Genetic Disorders
• Chapter 15: Treating Genetic Disorders and Using Genetics to Tailor Treatment
• Alleviating Genetic Disease through Gene Therapy
• Inserting Healthy Genes into the Picture
• Finding Vehicles to Get Genes to Work
• Progress on the Gene Therapy Front
• Utilizing Genetic Information for Precision Medicine
• Part 4: Genetics and Your World
• Chapter 16: Tracing Human History and the Future of Populations
• Genetic Variation Is Everywhere
• Breaking Down the Hardy-Weinberg Law of Population Genetics
• Mapping the Gene Pool
• Changing Forms over Time: The Genetics of Evolution
• Chapter 17: Solving Mysteries Using DNA
• Rooting through Your DNA to Find Your Identity
• Investigating the Scene: Where’s the DNA?
• Employing DNA to Catch Criminals (And Free the Innocent)
• It’s All Relative: Finding Family
• Chapter 18: DNA Sequencing: Decoding the Genome
• Sequencing: Reading the Language of DNA
• Sequencing Your Way to the Human Genome
• Trying on a Few Genomes
• Chapter 19: Genetic Makeovers: Using Genetic Engineering to Change the Genome
• Genetically Modified Organisms Are Everywhere
• Old Genes in New Places
• Looking at the GMO Menagerie
• Transgenic Plants
• Changing the Blueprint: Gene Editing
• Chapter 20: Giving Ethical Considerations Their Due
• Profiling Genetic Discrimination
• Ordering Up Designer Babies
• Ethical Issues Surrounding Genetic Testing
• Practicing Safe Genetic Treatments
• Genetic Property Rights
• Part 5: The Part of Tens
• Chapter 21: Ten Hot Issues in Genetics
• Direct-to-Consumer Genetic Testing
• Whole Exome Sequencing
• Whole Genome Sequencing
• Stem Cell Research
• The ENCODE Project
• Proteomics
• Gene Chips
• Evolution of Antibiotic Resistance
• Circumventing Mother Nature
• Genetics from Afar
• Chapter 22: Ten Pathways to a Career in Genetics
• Laboratory Technicians
• Graduate Student
• Post-doctoral Fellows
• Research Scientist
• College or University Professor
• Clinical Laboratory Director
• Clinical Geneticist
• Genetic Counselor
• Genetic Counseling Assistant
• Forensic Geneticist
• Index
• About the Authors
• Advertisement Page
• Connect with Dummies
• End User License Agreement