Efnisyfirlit

• Cover
• Front Matter
• Part I. Pharmaceutical Biotechnology: The Science, Techniques, and Important Concepts
• 1. Molecular Biotechnology: From DNA Sequence to Therapeutic Protein
• 2. Biophysical and Biochemical Characteristics of Therapeutic Proteins
• 3. Stability and Characterization of Protein- and Nucleotide-Based Therapeutics
• 4. Production and Purification of Recombinant Proteins
• 5. Formulation of Biologics Including Biopharmaceutical Considerations
• 6. Pharmacokinetics and Pharmacodynamics of Therapeutic Proteins and Nucleic Acids
• 7. Immunogenicity of Therapeutic Proteins
• 8. Monoclonal Antibodies: From Structure to Therapeutic Application
• 9. Genomics, Other “OMIC” Technologies, Precision Medicine, and Additional Biotechnology-Related Techniques
• 10. Economic Considerations in Medical Biotechnology
• 11. Biosimilars: Principles, Regulatory Framework, and Societal Aspects
• 12. An Evidence-Based Practice Approach to Evaluating Biotechnologically Derived Medications
• Part II. Pharmaceutical Biotechnology: Oligonucleotides, Genes and Cells/Cell Subunits, Vaccines—The Science, Techniques, and Clinical Use
• 13. Oligonucleotides and mRNA Therapeutics
• 14. Advanced Therapy Medicinal Products: Clinical, Non-clinical, and Quality Considerations
• 15. Vaccines
• Part III. Pharmaceutical Biotechnology: The Protein Products of Biotechnology and Their Clinical Use—Endogenous Proteins and Their Variations
• 16. Insulin
• 17. Hematopoietic Growth Factors
• 18. Recombinant Coagulation Factors and Thrombolytic Agents
• 19. Follicle-Stimulating Hormone
• 20. Human Growth Hormone
• 21. Recombinant Human Deoxyribonuclease I
• 22. Interferons and Interleukins
• Part IV. Pharmaceutical Biotechnology: The Protein Products of Biotechnology and Their Clinical Use—Monoclonal Antibodies and Their Variations
• 23. Antibody-Based Biotherapeutics in Cancer
• 24. Antibody-Based Biotherapeutics in Inflammatory Diseases
• 25. Monoclonal Antibodies in Solid Organ Transplantation
• 26. Antibody-Based Biotherapeutics in Migraine
• Back Matter