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• COVER
• TITLE PAGE
• ABOUT THE AUTHORS
• PREFACE
• OBJECTIVES
• LIMITED TIME—PROCESS OR PRODUCT DESIGN?
• FORMAT OF COURSEWARE AND SUPPORTING WEB SITE
• ADVICE TO STUDENTS AND INSTRUCTORS
• ACKNOWLEDGMENTS
• PART ONE INTRODUCTION TO PRODUCT AND PROCESS DESIGN
• CHAPTER 1 INTRODUCTION TO CHEMICAL PRODUCT DESIGN
• 1.0 OBJECTIVES
• 1.1 INTRODUCTION
• 1.2 THE DIVERSITY OF CHEMICAL PRODUCTS
• 1.3 PRODUCT DESIGN AND DEVELOPMENT
• 1.4 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 2 INTRODUCTION TO PROCESS DESIGN
• 2.0 OBJECTIVES
• 2.1 INTRODUCTION
• 2.2 EXPERIMENTS
• 2.3 PRELIMINARY PROCESS SYNTHESIS
• 2.4 NEXT PROCESS DESIGN TASKS
• 2.5 PRELIMINARY FLOWSHEET MASS BALANCES
• 2.6 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 3 DESIGN LITERATURE, STIMULATING INNOVATION, ENERGY, ENVIRONMENT, SUSTAINABILITY, SAFETY, ENGINEERING ETHICS
• 3.0 OBJECTIVES
• 3.1 DESIGN LITERATURE
• 3.2 STIMULATING INVENTION AND INNOVATION
• 3.3 ENERGY SOURCES
• 3.4 ENVIRONMENTAL PROTECTION
• 3.5 SUSTAINABILITY
• 3.6 SAFETY CONSIDERATIONS
• 3.7 ENGINEERING ETHICS
• 3.8 SUMMARY
• REFERENCES
• EXERCISES
• PART TWO DESIGN SYNTHESIS—PRODUCT AND PROCESSES
• CHAPTER 4 MOLECULAR AND MIXTURE DESIGN
• 4.0 OBJECTIVES
• 4.1 INTRODUCTION
• 4.2 FRAMEWORK FOR COMPUTER-AIDED MOLECULAR-MIXTURE DESIGN
• 4S-1 Liquid Blend Product Design
• 4S-2 Formulated Liquid Product Design
• 4S-3 Software for Molecular and Mixture Design
• 4.3 CASE STUDIES
• 4.4 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 5 DESIGN OF CHEMICAL DEVICES, FUNCTIONAL PRODUCTS, AND FORMULATED PRODUCTS
• 5.0 OBJECTIVES
• 5.1 INTRODUCTION
• 5.2 DESIGN OF CHEMICAL DEVICES AND FUNCTIONAL PRODUCTS
• 5.3 DESIGN OF FORMULATED PRODUCTS
• 5.4 DESIGN OF PROCESSES FOR B2C PRODUCTS
• 5.5 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 6 HEURISTICS FOR PROCESS SYNTHESIS
• 6.0 OBJECTIVES
• 6S-0 Introduction to Three Supplements for Chapter 6
• 6S-1 Hybrid Process-Group Based Process Synthesis
• 6S-2 Math Programming Superstructures for Process Synthesis
• 6S-3 ProCAFD, Computer-Aided Flowsheet Design
• 6.1 INTRODUCTION
• 6.2 RAW MATERIALS AND CHEMICAL REACTIONS
• 6.3 DISTRIBUTION OF CHEMICALS
• 6.4 SEPARATIONS
• 6.5 HEAT REMOVAL FROM AND ADDITION TO REACTORS
• 6.6 HEAT EXCHANGERS AND FURNACES
• 6.7 PUMPING, COMPRESSION, PRESSURE REDUCTION, VACUUM, AND CONVEYING OF SOLIDS
• 6.8 CHANGING THE PARTICLE SIZE OF SOLIDS AND SIZE SEPARATION OF PARTICLES
• 6.9 REMOVAL OF PARTICLES FROM GASES AND LIQUIDS
• 6.10 CONSIDERATIONS THAT APPLY TO THE ENTIRE FLOWSHEET
• 6.11 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 7 SIMULATION TO ASSIST IN PROCESS CREATION
• 7.0 OBJECTIVES
• 7.1 INTRODUCTION
• 7.2 PRINCIPLES OF PROCESS SIMULATION
• 7.3 PROCESS CREATION THROUGH PROCESS SIMULATION
• 7.4 CASE STUDIES
• 7.5 PRINCIPLES OF BATCH FLOWSHEET SIMULATION
• 7.6 SUMMARY
• REFERENCES
• EXERCISES
• NOTE
• CHAPTER 8 SYNTHESIS OF NETWORKS CONTAINING REACTORS
• 8.0 OBJECTIVES
• 8.1 INTRODUCTION
• 8.2 REACTOR MODELS IN THE PROCESS SIMULATORS
• 8.3 REACTOR NETWORK DESIGN USING THE ATTAINABLE REGION
• 8.4 REACTOR DESIGN FOR COMPLEX CONFIGURATIONS
• 8.5 LOCATING THE SEPARATION SECTION WITH RESPECT TO THE REACTOR SECTION
• 8.6 TRADE-OFFS IN PROCESSES INVOLVING RECYCLE
• 8.7 OPTIMAL REACTOR CONVERSION
• 8.8 RECYCLE TO EXTINCTION
• 8.9 SNOWBALL EFFECTS IN THE CONTROL OF PROCESSES INVOLVING RECYCLE
• 8.10 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 9 SYNTHESIS OF SEPARATION TRAINS
• 9.0 OBJECTIVES
• 9.1 INTRODUCTION
• 9.2 CRITERIA FOR SELECTION OF SEPARATION METHODS
• 9.3 SELECTION OF EQUIPMENT
• 9.4 SEQUENCING OF ORDINARY DISTILLATION COLUMNS FOR THE SEPARATION OF NEARLY IDEAL LIQUID MIXTURES
• 9.5 SEQUENCING OF OPERATIONS FOR THE SEPARATION OF NONIDEAL LIQUID MIXTURES
• 9.6 SEPARATION SYSTEMS FOR GAS MIXTURES
• 9.7 SEPARATION SYSTEMS FOR SOLID-FLUID MIXTURES
• 9.8 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 10 SECOND-LAW ANALYSIS
• 10.0 OBJECTIVES
• 10.1 INTRODUCTION
• 10.2 THE SYSTEM AND THE SURROUNDINGS
• 10.3 ENERGY TRANSFER
• 10.4 THERMODYNAMIC PROPERTIES
• 10.5 EQUATIONS FOR SECOND-LAW ANALYSIS
• 10.6 EXAMPLES OF LOST-WORK CALCULATIONS
• 10.7 THERMODYNAMIC EFFICIENCY
• 10.8 CAUSES OF LOST WORK
• 10.9 THREE EXAMPLES OF SECOND-LAW ANALYSIS
• 10.10 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 11 HEAT AND POWER INTEGRATION
• 11.0 OBJECTIVES
• 11.1 INTRODUCTION
• 11.2 MINIMUM UTILITY TARGETS
• 11.3 NETWORKS FOR MAXIMUM ENERGY RECOVERY
• 11.4 MINIMUM NUMBER OF HEAT EXCHANGERS
• 11.5 THRESHOLD APPROACH TEMPERATURE
• 11.6 OPTIMUM APPROACH TEMPERATURE
• 11.7 MULTIPLE UTILITIES
• 11.8 HEAT-INTEGRATED REACTORS AND DISTILLATION TRAINS
• 11.9 HEAT ENGINES AND HEAT PUMPS
• 11.10 SUMMARY
• 11S-1 MILP and MINLP Applications in HEN Synthesis
• 11S-2 Mass Integration
• REFERENCES
• EXERCISES
• CHAPTER 12 HEAT EXCHANGER DESIGN
• 12.0 OBJECTIVES
• 12.1 INTRODUCTION
• 12.2 EQUIPMENT FOR HEAT EXCHANGE
• 12.3 HEAT-TRANSFER COEFFICIENTS AND PRESSURE DROP
• 12.4 DESIGN OF SHELL-AND-TUBE HEAT EXCHANGERS
• 12.5 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 13 SEPARATION TOWER DESIGN
• 13.0 OBJECTIVES
• 13.1 OPERATING CONDITIONS
• 13.2 FENSKE-UNDERWOOD-GILLILAND (FUG) SHORTCUT METHOD FOR ORDINARY DISTILLATION
• 13.3 KREMSER SHORTCUT METHOD FOR ABSORPTION AND STRIPPING
• 13.4 RIGOROUS MULTICOMPONENT, MULTIEQUILIBRIUM-STAGE METHODS WITH A SIMULATOR
• 13.5 PLATE EFFICIENCY AND HETP
• 13.6 TOWER DIAMETER
• 13.7 PRESSURE DROP AND WEEPING
• 13.8 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 14 PUMPS, COMPRESSORS, AND EXPANDERS
• 14.0 OBJECTIVES
• 14.1 PUMPS
• 14.2 COMPRESSORS AND EXPANDERS
• 14.3 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 15 CHEMICAL REACTOR DESIGN
• 15.0 OBJECTIVES
• 15.1 INTRODUCTION
• 15.2 LIMITING APPROXIMATE MODELS FOR TUBULAR REACTORS
• 15.3 THE COMSOL CFD PACKAGE
• 15.4 CFD FOR TUBULAR REACTOR MODELS
• 15.5 NONISOTHERMAL TUBULAR REACTOR MODELS
• 15.6 MIXING IN STIRRED-TANK REACTORS
• 15.7 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 16 COST ACCOUNTING AND CAPITAL COST ESTIMATION
• 16.0 OBJECTIVES
• 16.1 ACCOUNTING
• 16.2 COST INDEXES AND CAPITAL INVESTMENT
• 16.3 CAPITAL INVESTMENT COSTS
• 16.4 ESTIMATION OF THE TOTAL CAPITAL INVESTMENT
• 16.5 PURCHASE COSTS OF THE MOST WIDELY USED PROCESS EQUIPMENT
• 16.6 PURCHASE COSTS OF OTHER CHEMICAL PROCESSING EQUIPMENT
• 16.7 EQUIPMENT COSTING SPREADSHEET
• 16.8 EQUIPMENT SIZING AND CAPITAL COST ESTIMATION USING ASPEN PROCESS ECONOMIC ANALYZER (APEA)
• 16.9 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 17 ANNUAL COSTS, EARNINGS, AND PROFITABILITY ANALYSIS
• 17.0 OBJECTIVES
• 17.1 INTRODUCTION
• 17.2 ANNUAL SALES REVENUES, PRODUCTION COSTS, AND THE COST SHEET
• 17.3 WORKING CAPITAL AND TOTAL CAPITAL INVESTMENT
• 17.4 APPROXIMATE PROFITABILITY MEASURES
• 17.5 TIME VALUE OF MONEY
• 17.6 CASH FLOW AND DEPRECIATION
• 17.7 RIGOROUS PROFITABILITY MEASURES
• 17.8 PROFITABILITY ANALYSIS SPREADSHEET
• 17.9 SUMMARY
• REFERENCES
• EXERCISES
• PART THREE DESIGN ANALYSIS—PRODUCT AND PROCESS
• CHAPTER 18 SIX-SIGMA DESIGN STRATEGIES
• 18.0 OBJECTIVES
• 18.1 INTRODUCTION
• 18.2 SIX-SIGMA METHODOLOGY IN PRODUCT DESIGN AND MANUFACTURING
• 18.3 EXAMPLE APPLICATIONS
• 18S Penicillin Plant Fermenter and Extraction Models
• 18.4 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 19 BUSINESS DECISION MAKING IN PRODUCT DEVELOPMENT
• 19.0 OBJECTIVES
• 19.1 INTRODUCTION
• 19.2 ECONOMIC ANALYSIS
• 19.3 MAKE-OR-BUY DECISIONS
• 19.4 MICROECONOMICS OF PRODUCT DEVELOPMENT
• 19.5 COMPANY AND SOCIETAL FACTORS AFFECTING PRODUCT DEVELOPMENT
• 19.6 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 20 PLANTWIDE CONTROLLABILITY ASSESSMENT
• 20.0 OBJECTIVES
• 20.1 INTRODUCTION
• 20.2 CONTROL SYSTEM CONFIGURATION
• 20.3 QUALITATIVE PLANTWIDE CONTROL SYSTEM SYNTHESIS
• 20.4 SUMMARY
• 20S Flowsheet Controllability Analysis
• REFERENCES
• EXERCISES
• CHAPTER 21 DESIGN OPTIMIZATION
• 21.0 OBJECTIVES
• 21.1 INTRODUCTION
• 21.2 GENERAL FORMULATION OF THE OPTIMIZATION PROBLEM
• 21.3 CLASSIFICATION OF OPTIMIZATION PROBLEMS
• 21.4 LINEAR PROGRAMMING (LP)
• 21.5 NONLINEAR PROGRAMMING (NLP) WITH A SINGLE VARIABLE
• 21.6 CONDITIONS FOR NONLINEAR PROGRAMMING (NLP) BY GRADIENT METHODS WITH TWO OR MORE DECISION VARIABLES
• 21.7 OPTIMIZATION ALGORITHM
• 21.8 FLOWSHEET OPTIMIZATIONS—CASE STUDIES
• 21.9 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 22 OPTIMAL DESIGN AND SCHEDULING OF BATCH PROCESSES
• 22.0 OBJECTIVES
• 22.1 INTRODUCTION
• 22.2 DESIGN OF BATCH PROCESS UNITS
• 22.3 DESIGN OF REACTOR–SEPARATOR PROCESSES
• 22.4 DESIGN OF SINGLE-PRODUCT PROCESSING SEQUENCES
• 22.5 DESIGN ON MULTIPRODUCT PROCESSING SEQUENCES
• 22.6 SUMMARY
• REFERENCES
• EXERCISES
• PART FOUR DESIGN REPORTS—PRODUCT AND PROCESS
• CHAPTER 23 WRITTEN REPORTS AND ORAL PRESENTATIONS
• 23.0 OBJECTIVES
• 23.1 CONTENTS OF THE WRITTEN REPORT
• 23.2 PREPARATION OF THE WRITTEN REPORT
• 23.3 ORAL DESIGN PRESENTATIONS
• 23.4 AWARD COMPETITION
• 23.5 SUMMARY
• REFERENCES
• PART FIVE CASE STUDIES—PRODUCT AND PROCESS DESIGNS
• CHAPTER 24 CASE STUDY 1—HOME HEMODIALYSIS DEVICES
• 24.0 OBJECTIVES
• 24.1 HEMODIALYSIS TECHNOLOGY
• 24.2 DESIGN SPECIFICATIONS OF HOME HEMODIALYSIS DEVICE
• 24.3 SUMMARY
• REFERENCES
• PATENTS—HEMODIALYSIS DEVICES—HOLLOW-FIBER MEMBRANES
• PATENTS—HEMODIALYSIS DEVICES—DIALYSATE REGENERATION
• PATENTS—HEMODIALYSIS DEVICES—ALARMS/USER INTERFACE
• EXERCISES
• CHAPTER 25 CASE STUDY 2—HIGH THROUGHPUT SCREENING DEVICES FOR KINASE INHIBITORS
• 25.0 OBJECTIVES
• 25.1 BACKGROUND TECHNOLOGY FOR HIGH THROUGHPUT SCREENING OF KINASE INHIBITORS
• 25.2 PRODUCT CONCEPT
• 25.3 PROTOTYPING
• 25.4 PRODUCT DEVELOPMENT
• 25.5 SUMMARY
• REFERENCES
• PATENTS
• EXERCISES
• CHAPTER 26 CASE STUDY 3—DIE ATTACH ADHESIVE: A CASE STUDY OF PRODUCT DEVELOPMENT
• 26.0 OBJECTIVES
• 26.1 BACKGROUND OF TECHNOLOGY
• 26.2 MARKET STUDY
• 26.3 PRODUCT DESIGN
• 26.4 PROCESS DESIGN
• 26.5 PROTOTYPING
• 26.6 ESTIMATION OF PRODUCT COST
• 26.7 SUMMARY
• REFERENCES
• EXERCISES
• CHAPTER 27 CASE STUDY 4—AMMONIA PROCESS
• 27.0 OBJECTIVES
• 27.1 INTRODUCTION
• 27.2 INITIAL BASE CASE DESIGN
• 27.3 DESIGN REFINEMENT
• REFERENCES
• EXERCISES
• NOTE
• CHAPTER 28 CASE STUDY 5—WINE AERATOR DEVICE
• CHAPTER 29 CASE STUDY 6—FAUCET WATER PURIFIER
• CHAPTER 30 CASE STUDY 7—DOMESTIC DEHUMIDIFIER
• CHAPTER 31 CASE STUDY 8—VITAMIN C TABLETS
• CHAPTER 32 CASE STUDY 9—CONDUCTIVE INK FOR PRINTED ELECTRONICS
• CHAPTER 33 CASE STUDY 10—PVB INTERLAYER FOR SMART WINDOW
• APPENDIX I RESIDUE CURVES FOR HETEROGENEOUS SYSTEMS
• APPENDIX II DESIGN PROBLEM STATEMENTS BY AREA
• APPENDIX III MATERIALS OF CONSTRUCTION
• TABLE OF ACRONYMS
• AUTHOR INDEX
• SUBJECT INDEX
• END USER LICENSE AGREEMENT