Description
Efnisyfirlit
- Instructions for online access
- Cover image
- Title page
- Copyright
- Contents
- Preface
- Online Study for Students
- 1 Why Study Microbiology?
- A Note on Emerging and Re-emerging Infections
- About This Book
- Further Reading
- Part 1 General microbiology
- 2 Bacterial Structure and Taxonomy
- Eukaryotes and Prokaryotes
- Morphology
- Taxonomy
- Review Questions (Answers on p. 388)
- Further Reading
- 3 Bacterial Physiology and Genetics
- Bacterial Physiology
- Bacterial Genetics
- Recombinant DNA Technology in Microbiology
- The Era of ‘-omics’
- Review Questions (answers on p. 388)
- Further Reading
- 4 Viruses and Prions
- Structure
- Taxonomy
- Viral Replication
- Pathogenesis of Viral Infections
- Cellular Antiviral Response
- Prions and Prion Diseases
- Review Questions (answers on p. 388)
- Further Reading
- 5 Pathogenesis of Microbial Disease
- General Aspects of Infection
- Pathogenesis of Bacterial Disease
- Pathogenesis of Viral Disease
- Pathogenesis of Fungal Disease
- Koch’s Postulates
- Review Questions (Answers on p. 388)
- Further Reading
- 6 Diagnostic Microbiology and Laboratory Methods
- Diagnostic Microbiology
- Laboratory Methods
- Bacterial Identification
- Immunological Methods
- Laboratory Investigations Related to Antimicrobial Therapy
- Appropriate Specimens in Medical Microbiology
- Laboratory Isolation and Identification of Viruses
- Diagnosis of Fungal Infections
- Review Questions (Answers on p. 388)
- Further Reading
- 7 Antimicrobial Chemotherapy
- Bacteriostatic and Bactericidal Antimicrobial Agents
- Principles of Antimicrobial Therapy
- Pharmacodynamics of Antimicrobials
- Failure of Antimicrobial Therapy
- Antimicrobials Commonly Used in Dentistry
- Antibacterial Agents
- Antifungal Agents
- Antiviral Agents
- Review Questions (Answers on p. 388)
- Further Reading
- Part 2 Basic immunology
- 8 The Immune System and the Oral Cavity
- The Immune System: General Considerations
- The Innate Immune System
- The Adaptive Immune System
- Cells of the Immune System
- Oral Defence Mechanisms
- Innate Immune Mechanisms
- The Oral Mucosal Epithelium
- Adaptive Immunity in Oral Health and Disease
- Review Questions (Answers on p. 388)
- Further Reading
- 9 The Immune Response
- Antibodies
- Cytokines
- B Cell Activation
- Antigen Processing and Presentation
- T-Helper Subsets
- Target Cell Killing
- Activation of Macrophages
- Regulation of the Immune Response
- Immunological Memory
- Review Questions (Answers on p. 389)
- Further Reading
- 10 Immunity and Infection
- Immunity to Bacteria
- Immunity to Viruses
- Immunity to Parasites
- Immunity to Fungi
- Vaccination
- ‘-omics’ Developments Impacting Oral Immunology
- Review Questions (Answers on p. 389)
- Further Reading
- Part 3 Microbes of relevance to dentistry
- 11 Streptococci, Staphylococciand Enterococci
- Streptococci
- Staphylococci
- Enterococci
- Micrococci
- Review Questions (Answers on p. 389)
- Further Reading
- 12 Lactobacilli, Corynebacteria and Propionibacteria
- Lactobacilli
- Corynebacteria
- Propionibacteria
- Review Questions (Answers on p. 389)
- Further Reading
- 13 Actinomycetes, Clostridia and Bacillus Species
- Actinomycetes
- Nocardia
- Clostridia
- Bacillus
- Review Questions (Answers on p. 389)
- Further Reading
- 14 Neisseriaceae, Veillonella, Parvobacteria and Capnocytophaga
- Neisseriaceae
- Veillonella
- Parvobacteria
- Haemophilus Species
- Bordetella
- Review Questions (Answers on p. 389)
- Further Reading
- 15 Enterobacteria
- General Characteristics of Enterobacteria
- Eschericheae
- Salmonellae
- Shigellae
- Klebsielleae
- Pseudomonads
- Review Questions (Answers on p. 389)
- Further Reading
- 16 Vibrios, Campylobacters and Wolinella
- Vibrios
- Campylobacters
- Wolinella
- Review Questions (Answers on p. 390)
- Further Reading
- 17 Bacteroides, Tannerella, Porphyromonas and Prevotella
- Bacteroides
- Tannerella
- Porphyromonas
- Prevotella
- Review Questions (Answers on p. 390)
- Further Reading
- 18 Fusobacteria, Leptotrichia and Spirochaetes
- Fusobacteria
- Leptotrichia
- Spirochaetes
- Treponema
- Borrelia
- Leptospira
- Review Questions (Answers on p. 390)
- Further Reading
- 19 Mycobacteria and Legionellae
- Mycobacteria
- Legionella
- Further Reading
- Review Questions (Answers on p. 390)
- 20 Chlamydiae, Rickettsiae and Mycoplasmas
- Chlamydiae
- Rickettsiae
- Mycoplasmas
- Further Reading
- Review Questions (Answers on p. 390)
- 21 Viruses of Relevance to Dentistry
- DNA Viruses
- RNA Viruses
- Viruses and Cancer
- Further Reading
- Review Questions (Answers on p. 390)
- 22 Fungi of Relevance to Dentistry
- Morphology
- Reproduction
- Classification
- Cultural Requirements
- Pathogenicity
- Human Mycoses
- Yeasts
- Filamentous and Dimorphic Fungi and Oral Disease
- Review Questions (Answers on p. 390)
- Further Reading
- Part 4 Systemic Infections of relevance to dentistry
- 23 Infections of the Respiratory Tract
- Normal Flora
- Important Pathogens of the Respiratory Tract
- Infections of the Upper Respiratory Tract
- Infections of the Paranasal Sinuses and the Middle Ear
- Infections of the Trachea and Bronchi
- Lung Infections
- Severe Acute Respiratory Syndrome (SARS) and Coronavirus Disease 2019 (COVID-19)
- Fungal Infections of the Lower Respiratory Tract
- Respiratory Infections and Dentistry
- Review Questions (Answers on p. 390)
- Further Reading
- 24 Infections of the Cardiovascular System
- Bacteraemia, Septicaemia and Sepsis Syndrome
- Infections of the Heart
- British and US Guidelines on Prophylaxis Against Infective Endocarditis in Patients Undergoing Interventional Procedures
- Dental Procedures That Need Antibiotic Prophylaxis
- Review Questions (Answers on p. 390)
- Further Reading
- 25 Infections of the Central Nervous and Locomotor Systems
- Infections of the Central Nervous System
- Infections of the Locomotor System
- Arthroplasties and Antibiotic Prophylaxis for Dental Procedures
- Review Questions (Answers on p. 391)
- Further Reading
- 26 Infections of the Gastrointestinal Tract
- Normal Flora
- Common Diarrhoeal Diseases
- Less Common and Uncommon Diarrhoeal Diseases
- Nonbacterial Causes of Diarrhoea
- Review Questions (Answers on p. 391)
- Further Reading
- 27 Infections of the Genitourinary Tract
- Normal Flora and the Natural Defences of the Genitourinary Tract
- Sexually Transmitted Infections
- Urinary Tract Infections
- Dentistry and Genitourinary Infections
- Review Questions (Answers on p. 391)
- Further Reading
- 28 Skin and Wound Infections
- Normal Flora
- Skin Infections
- Wound Infections
- Review Questions (Answers on p. 391)
- Further Reading
- 29 Viral Hepatitis
- Signs and Symptoms of Hepatitis
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D (Delta Hepatitis)
- Hepatitis E
- Hepatitis Viruses of Unclear Pathogenicity
- Review Questions (Answers on p. 391)
- Further Reading
- 30 Human Immunodeficiency Virus Infection, AIDS and Infections in Compromised Patients
- Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome
- Human Immunodeficiency Virus
- Acquired Immune Deficiency Syndrome
- Prevention of HIV Infection
- Infections in Compromised Patients
- Xerostomia and Infection
- Review Questions (Answers on p. 391)
- Further Reading
- Part 5 Oral microbiota and oral infections
- 31 Oral Microbiota and the Oralome
- Oral Microbiome and the Oral Microbiota
- Oral Microbiota
- Oral Bacteriome
- Oral Mycobiome
- Oral Virome
- Oral Phageome
- Oral Archaeome
- Oral Protozome
- The Oral Ecosystem
- The Plaque Biofilm
- Review Questions (Answers on p. 391)
- Further Reading
- 32 Microbiology of Dental Caries
- Epidemiology
- Classifications
- Diagnosis
- Aetiology
- Management of Dental Caries
- Review Questions (Answers on p. 392)
- Further Reading
- 33 Microbiology of Periodontal Disease
- The Periodontium
- Classification of Periodontal Disease
- The Progression From Gingivitis to Periodontitis
- Relationship Between Chronic Marginal Gingivitis and Periodontitis
- Acute Necrotizing Ulcerative Gingivitis (ANUG)
- Pericoronitis
- Peri-implant Microbiology
- Clinical Implications of Microbiological Tests in Periodontal Disease
- Review Questions (Answers on p. 392)
- Further Reading
- 34 Dentoalveolar and Endodontic Infections
- Natural History of Dentoalveolar Infections
- Source of Microorganisms
- Apical Dentoalveolar Abscess
- Ludwig’s Angina
- Pericoronitis (See Chapter 33.)
- Periodontal Abscess
- Suppurative Osteomyelitisof the Jaws
- Cervicofacial Actinomycosis
- Facial Lacerations
- Endodontic Infections
- Review Questions (answers on p. 392)
- Further Reading
- 35 Oral Mucosal and Salivary Gland Infections
- Oral Mucosal Infections
- Oral Manifestations of Systemic Mycoses
- Oral Viral Infections
- Oral Manifestations of Bacterial Infections
- Salivary Gland Infections
- Review Questions (Answers on p. 392)
- Further Reading
- Part 6 Cross-infection and control
- 36 General Principles of Infection Control, Standard Precautions and Transmission-Based Precautions
- General Principles of Infection Control
- Routes of Infection
- Standard Infection Control Precautions
- Review Questions (Answers on p. 392)
- Further Reading
- 37 Standard Infection Control Procedures in Dentistry Part I: Personal Protection, Sharps Injuries Protocol and Immunization
- Practice Management and Staff Development
- Infection Control: Specific Practical Features
- Review Questions (Answers on p. 392)
- Further Reading
- 38 Standard Infection Control Procedures in Dentistry Part II: Sterilization, Disinfection and Antisepsis, with a Summary of Transmission-Based Infection Control Procedures
- Sterilization, Disinfection and Antisepsis
- Decontamination
- Decontamination of Instruments
- Sterilization
- Disinfection
- Step 1
- Step 2
- Environmental Disinfection
- Dental Unit Water Lines: Disinfection and Management
- Recommendations on Care of Handpieces and Other Devices Attached to Air and Water Lines
- Dental Radiology
- Laboratory Asepsis
- Office/Surgery Design and Maintenance
- Instrument Recirculation and Office Design
- Disposal of Clinical Waste
- Transmission-Based Precautions
- Contact Precautions: For Ambulatory Clinic Settings
- Droplet Precautions: For Ambulatory Clinic Settings
- Airborne Precautions: For Ambulatory Clinic Settings
- Review Questions (Answers on p. 392)
- Further Reading
- Answers to Review Questions
- Glossary of Terms and Abbreviations
- Index
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